Immune Deficiency in CHARGE Association

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Immune deficiency in CHARGE association.

CHARGE association is the sporadic, non-random concurrence of Coloboma of the eye, Heart anomalies, choanal Atresia, Retardation of growth and development, Genitourinary anomalies, Ear anomalies and deafness (CHARGE association). Other abnormalities have also been reported in small numbers of patients with CHARGE association. The molecular basis of the CHARGE association is not clear. The spect...

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Recurrent meningitis in association with common variable immune deficiency.

Recurrent meningitis in children is unusual and usually associated with a predisposing factor like immune-deficiency disorder or cranio-spinal defect. We report a case of recurrent meningitis in association with Common Variable Immune deficiency.

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Host Immune Deficiency in Immune Complex Nephritis1

Evidence is reviewed that indicates that an immune deficiency state may underlie patients with immune complex nephritis. Studies in several laboratories provide data that show defective immune function in patients with nephritis at the following loci: defective immunoglobulin production, impaired monocyte Fc and C3b receptor function, diminished complement biosynthesis, and decreased mesangial ...

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CHARGE association.

CHARGE association is a heterogeneous condition that affects several organ systems, including the eye, ear, nose, heart, and genitals. Hearing loss is a common finding in CHARGE association; therefore, audiologists and otolaryngologists need to be familiar with this relatively common entity.

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Immune deficiency diseases.

Paediatricians have long been deeply concerned with problems of infection. The sharp decrease in childhood mortality in recent decades in highly developed countries is mainly due to progress in preventing and treating infection: for example, in Switzerland in 1973 there were about 88 000 births and only 16 deaths due to infection in children aged between 2 and 4 years in contrast to 76 killed b...

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ژورنال

عنوان ژورنال: Clinical Medicine & Research

سال: 2003

ISSN: 1539-4182,1554-6179

DOI: 10.3121/cmr.1.1.43